Skelaxin is a muscle relaxant used to treat pain caused by muscle spasms.

About Skelaxin

Skelaxin is a skeletal muscle relaxant used to relieve the pain of muscle injuries, spasms, sprains, and strains. Skelaxin is recommended as a supplement to physical therapy, rest, or other treatments your doctor may recommend, and it will not replace these treatments. Do not overuse injured muscles while under the effects of Skelaxin, as this may result in further injury and a prolonged recovery time.

Skelaxin is only available by prescription.

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Skelaxin Side Effects

Mild Skelaxin Side Effects: Blurred or double vision, clumsiness, dizziness, drowsiness, faintness, or light headedness are the most common side effects, but are not usually a cause for concern. Less common, though not generally dangerous, side effects include abdominal cramps, confusion, excitement or restlessness, flushing, headache, heartburn, hiccups, insomnia, irritability, irritable bowel, weakness.

Serious Skelaxin Side Effects: Bloody urine, bloody or black stools, chills, cough, depression, difficult urination, difficulty breathing, eyes that are red, bloodshot, or stinging, fainting, fast breathing, fever, hives, itching, paradoxical muscle cramping, racing heartbeat or tightness in the chest, rash, sore throat, sores in mouth, stuffy nose, swelling around eyes, swollen or tender glands, unusual fatigue, unusual weakness, vomiting bloody or black material, yellow eyes or skin. These side effects range from uncommon to rare, but should you experience any of them while taking Skelaxin, contact your doctor or seek medical attention immediately.

Cautions: This medication may not be an appropriated treatment for all individuals, or your doctor may want to take certain precautions while you are using Skelaxin. Be especially sure to discuss such considerations with your doctor if you have a history of any of the following:

  • Allergies: If you have ever had an allergic reaction to Skelaxin or another skeletal muscle relaxant, be sure to inform your doctor. This medication may not be right for you.
  • Blood disease caused by reaction to a medication: This condition may be worsened.
  • Diabetes: Skelaxin can cause false results in certain urine tests for sugar levels. Inform laboratory personnel or your doctor in advance of a test.
  • Epilepsy: Related drugs have been known to cause convulsions. Though the risk of Skelaxin causing a convulsion is extremely small, there is the potential that drugs of the same class can cause similar reactions.
  • History of drug abuse or dependence: While Skelaxin may produce mild physical withdrawal symptoms, it is not generally a drug of abuse. Addiction prone individuals should still be cautious with this treatment and discuss the issue with their doctors.
  • Kidney or liver disease: Your doctor will determine if this medication is safe for you depending on your condition, but will likely suggest less frequent dosing if prescribed.
  • Porphyria: This is not a safe medication for porphyria, you will need to use another treatment.

Skelaxin Interactions

As a central nervous system depressant, Skelaxin (metaxalone) should be combined carefully, if at all, with any product which causes drowsiness. If you are taking any other medication, particularly those listed below, speak to your doctor about potential interactions.

  • Alcohol - Do not take alcohol while you are using metaxalone. There is an increased risk of side effects like drowsiness, unconsciousness, or overdose.
  • Benzodiazepines (a class of antidepressants, anti-panic agents, and muscle relaxants) such as Ativan (lorazepam), Valium (diazepam), Halcion (triazolam), Restoril (temazepam), Librium (chlordiazepoxide), Xanax (alprazolam), Tranxene-SD (clorazepate), Paxipam (halazepam), ProSom (estazolam), Klonopin (clonazepam), and others, should be used cautiously with metaxalone.
  • Central Nervous System Depressants - Any prescription medication, over the counter medication, or herbal supplement that may cause drowsiness. These medications should be used with caution while taking metaxalone as you may become oversedated. Consult your doctor or pharmacist to be sure that your treatment is as safe as possible.
  • Desyrel (trazodone) - Risk of additive CNS depression.
  • Narcotic pain medication like Codeine, Demerol (meperidine), Buprenex (buprenorphine), Darvon (propoxyphene), Dilaudid (hydromorphone), MS Contin or Kadian (morphine), nalbuphine, OxyContin (oxycodone), Percocet (oxycodone and acetaminophen), Stadol (butorphanol), Talwin compound (pentazocine), or Vicodin (hydrocodone and acetaminophen), Vicoprofen (hydrocodone and ibuprofen) may increase the central nervous system depressant effects of metaxalone.
  • Norflex (orphenadrine) - Risk of oversedation.
  • Sedatives like Butalbital, Fioricet (butalbital, acetaminophen, and caffeine), Fiorinal, Phenobarbitol, Seconal, or other barbiturates may cause over sedation in combination with metaxalone.
  • Skeletal muscle relaxants of any other type, such as Soma (carisoprodol), Robaxin (methocarbamol), or Flexeril (cyclobenzaprine) may overly depress the central nervous system when combined.
  • Sleep medication like Ambien (zolpidem), Sonata (zaleplon), or over the counter sleeping pills may cause over sedation when combined with muscle relaxants.
  • Tranquilizers like Haldol (haloperidol), Mellaril (thioridazine), or Thorazine (chlorpromazine) could cause oversedation when mixed with metaxalone.
  • Tricyclic antidepressants such as Elavil (amitriptyline), Asendin (amoxapine), Anafranil (clomipramine), Pertofrane or Norpramin (desipramine), Sinequan (doxepin), Tofranil (imipramine), Aventyl or Pamelor (nortriptyline), Vivactil (protriptyline), and Surmontil (trimipramine), may increase the central nervous system suppressant effects from either the antidepressant, or the metaxalone.
  • Ultram (tramadol) - This pain reliever may over sedate you if taken in combination with metaxalone.

Skelaxin Dosages

The Skelaxin brand of metaxalone comes in 400 mg scored, pink tablets. The general dosage for individuals over 12 years of age is two tablets 3-4 times daily, as needed. Do not exceed your doctor's dosage guidelines, or take double doses of this medication.

Skelaxin Directions

Store Skelaxin away from direct light and heat. Store in a dry location; avoid storing it in the bathroom, near sinks, or other areas where it may become damp. Do not use after the expiration date.

Keep Skelaxin away from children; both when storing it, and when discarding any unused medication.

Skelaxin may cause drowsiness or disorientation, and you should familiarize yourself with your reaction to it before engaging in potentially hazardous activities. Be cautious if you plan to drive or operate heavy machinery, avoid these activities if you find yourself feeling tired or experience slowed reactions.

Skelaxin and Pregnancy

Skelaxin has not been tested for safety in pregnant women. For these reasons, this medication should not be prescribed to pregnant women, or women who intend to become pregnant.

This medication also appears in breast milk and has not been studied in nursing infants. It is not recommended for nursing mothers, as it has not been shown to be safe for babies.

Skelaxin and Children

Skelaxin has not been tested for safety in children under 12.

Skelaxin and Seniors

Skelaxin has not been tested in older adults, and there is no information indicating that it works differently in seniors. However, as with other central nervous system depressants, seniors should be careful that they do not become oversedated or lose their balance while taking Skelaxin. Be sure to work out a medication schedule with your doctor or pharmacist to be sure that drug interactions and overlapping side effects are minimized